Xerostomia relief

October 13, 2008 11:00 AM Eastern Daylight Time
Introducing Salese™ — A New Soft Lozenge for Dry Mouth Sufferers
SANTA CLARA, Calif.--(BUSINESS WIRE)--Nuvora has introduced Salese™ (formerly Saleve), a revolutionary new soft lozenge for dry mouth sufferers that delivers moisture-retaining and bacteria-fighting ingredients for an hour or longer.
Dry mouth affects at least one in ten adults in the general population. In those over 65 years, the prevalence approaches 25 percent and in institutionalized elders the rates may be as high as 45-50 percent. Almost 40 percent of Florida residents 65+ years have dry mouth.
Dry mouth can cause serious health problems and it is estimated that over 1100 prescription and over-the-counter drugs have the potential to cause dry mouth. These include antacids, decongestants, antihistamines, antihypertensives, antidepressants and diuretics. Dry mouth may also result from Sjogren's syndrome, radiation treatment for head and neck cancers and salivary gland disease.
Traditional treatments for dry mouth have included sugar-free gum or candy, frequent sips of water, oral rinses as well as taking good care of teeth and gums. The ingredients in conventional mouth rinses, gums and mints are flushed away too quickly, limiting their effectiveness.
Now there's a new way to help dry mouth sufferers--Salese™, a long-lasting soft lozenge.
The key to Salese's long-lasting properties is Nuvora's patented Sustained Release Technology--SuRe™. A unique polymer combined with essential oils, Xylitol and a moisture-retaining ingredient creates an extended contact time in the mouth to fight bacteria and help dry mouth sufferers. Patients simply place Salese in their mouth, without biting or chewing, and let it slowly dissolve for an hour or longer.
Because Salese™ is a sustained release product, active ingredients (including Xylitol) are delivered efficiently and continuously in small doses — up to 1,000 times less than conventional mouthwash. The extended contact with beneficial agents increases both the oral hygiene benefits and the fresh mouth-feel essential to those suffering from Dry Mouth. Patients require less product during the course of a day and derive greater benefits, with no exposure to highly concentrated ingredients. Salese is sugar and alcohol free — less than one calorie — and helps maintain a healthy pH balance in the mouth.
It has long been recognized that dental biofilm plays a major role in the etiology of gingivitis, periodontitis, and caries. Although dental biofilm cannot be eradicated, the plaque it forms and its deleterious effects can be controlled with proper and diligent oral hygiene.
Bacteria begin to re-colonize on tooth surfaces immediately after a thorough dental prophylaxis, thereby reinitiating the process of plaque formation. And unfortunately, the active agents contained in short-lived antiseptic mouth rinses, chewing gums and breath mints dissipate or are flushed away quickly. As a consequence of their low residence time in the mouth, they barely affect the biofilm surface. They do not reside in the mouth long enough to allow their active agents to penetrate and dissolve biofilm, whose formidable barrier protects pathogenic and non-pathogenic microorganisms.
Understanding the requirement for long-term delivery of beneficial agents inside the mouth, Nuvora scientists developed the revolutionary SuRe™ (Sustained Release) technology that ensures that active agents remain in contact with biofilm for a sufficiently long time (one hour or longer) to materially impede its formation. The end result is long-lasting lozenges that continuously deliver ingredients, over long periods of time, to promote oral and dental health, and freshen breath.
The ingredients used in Nuvora lozenges are generally regarded as safe (GRAS). They kill bacteria, capture the malodors they cause, and impede the formation of biofilm. Evidence shows that lowering bacteria in the mouth promotes cleaner teeth and fresher breath, and reduces the risk of caries, gingivitis, periodontitis, and tooth loss. It also offers the added advantage of improving systemic health as it is now well known that inflammation of gums results in leakage of bacteria and inflammation-inducing compounds into the blood stream, increasing the risk of systemic diseases, including heart disease.
Availability: Consumers can buy Salese™ at the company's website www.nuvorainc.com or by calling Nuvora's toll-free number: 1-877-530-9811. Salese™ is an over-the-counter product and retailers can contact the company to purchase. Dental offices can purchase sample bags at the company's website or by calling the company.